Ro 22-5417, a new clavam antibiotic from Streptomyces clavuligerus. III. Absolute stereochemistry.
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چکیده
منابع مشابه
Aldecalmycin, a new antimicrobial antibiotic from Streptomyces.
A new antibiotic, aldecalmycin, has been discovered in the culture broth of Streptomyces sp. MJ147-72F6. Aldecalmycin was purified by solvent extraction, Diaion HP-20 chromatography, silica gel chromatography, Sephadex LH-20 chromatography, HPLC and centrifugal partition chromatography. The *H and 13C NMRspectra of aldecalmycin showed the presence of keto-enol tautomers. Aldecalmycin is equipot...
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The claR of Streptomyces clavuligerus in the clavulanic acid gene cluster encodes a transcriptional regulator that controls clavulanic acid biosynthesis. The main goal of this study was isolation and molecular detection of the claR gene and its cloning in the Streptomyces specific vector (pMA:: hyg). By cinsideration of the claR gene’s start codon, the specific primers were designed. After geno...
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ژورنال
عنوان ژورنال: The Journal of Antibiotics
سال: 1983
ISSN: 0021-8820,1881-1469
DOI: 10.7164/antibiotics.36.217